.Pharmacolibrary.Drugs.ATC.N.N05AB06

Information

name:Trifluoperazine
ATC code:N05AB06
route:oral
compartments:2
dosage:5mg
volume of distribution:10L
clearance:15L/h
other parameters in model implementation

Trifluoperazine is a typical antipsychotic drug of the phenothiazine class, primarily used to treat schizophrenia and other psychotic disorders. It can also be used in the short-term management of anxiety. It is still approved and listed in some formularies, although use has declined with the advent of atypical antipsychotics.

Pharmacokinetics

Pharmacokinetic model parameters for trifluoperazine in healthy adult volunteers, oral administration.

References

  1. Midha, KK, et al., & McKay, G (1988). A pharmacokinetic study of trifluoperazine in two ethnic populations. Psychopharmacology 95(3) 333–338. DOI:10.1007/BF00181943 PUBMED:https://pubmed.ncbi.nlm.nih.gov/3137618

Revisions


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