.Pharmacolibrary.Drugs.ATC.N.N05AH05 .Pharmacolibrary.Drugs.ATC.N.N05AH05| name: | Asenapine | |
| ATC code: | N05AH05 | route: | sublingual |
| compartments: | 2 | |
| dosage: | 5 | mg |
| volume of distribution: | 20.0 | L |
| clearance: | 52.0 | L/h |
| other parameters in model implementation | ||
Asenapine is an atypical antipsychotic drug indicated for the treatment of schizophrenia and bipolar disorder. It acts as an antagonist at multiple serotonergic, dopaminergic, and adrenergic receptors. It is approved and currently used as a sublingual or transdermal medication.
Healthy adult subjects, sublingual administration, single dose
Dogterom, P, et al., & Troyer, MD (2018). Asenapine pharmacokinetics and tolerability in a pediatric population. Drug design, development and therapy 12 2677–2693. DOI:10.2147/DDDT.S171475 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30214156