.Pharmacolibrary.Drugs.ATC.N.N05AH05_1

Information

name:Asenapine_1
ATC code:N05AH05_1
route:oral
n-compartments2

Asenapine is an atypical antipsychotic drug indicated for the treatment of schizophrenia and bipolar disorder. It acts as an antagonist at multiple serotonergic, dopaminergic, and adrenergic receptors. It is approved and currently used as a sublingual or transdermal medication.

Pharmacokinetics

Healthy adult subjects, oral (swallowed) administration, single dose for comparison

References

  1. Dogterom, P, et al., & Troyer, MD (2018). Asenapine pharmacokinetics and tolerability in a pediatric population. Drug design, development and therapy 12 2677–2693. DOI:10.2147/DDDT.S171475 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30214156

  2. Rado, J, & Janicak, PG (2012). Pharmacological and clinical profile of recently approved second-generation antipsychotics: implications for treatment of schizophrenia in older patients. Drugs & aging 29(10) 783–791. DOI:10.1007/s40266-012-0009-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23018584

Revisions


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