name: | Amisulpride |
ATC code: | N05AL05 | route: | oral |
n-compartments | 2 |
Amisulpride is an atypical antipsychotic medication primarily used to treat schizophrenia and, in some countries, depressive disorders. It acts mainly as a selective dopamine D2 and D3 receptor antagonist. Amisulpride is approved and marketed in several countries, but not in the United States.
Pharmacokinetics observed in healthy adult volunteers following oral administration.
Cao, SS, et al., & Zhang, BK (2017). Pharmacokinetics and relative bioavailability of a generic amisulpride tablet in healthy Chinese volunteers . International journal of clinical pharmacology and therapeutics 55(10) 825–831. DOI:10.5414/CP203000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28793958
Hamon-Vilcot, B, et al., & Piette, F (1998). Safety and pharmacokinetics of a single oral dose of amisulpride in healthy elderly volunteers. European journal of clinical pharmacology 54(5) 405–409. DOI:10.1007/s002280050483 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9754984
Täubel, J, et al., & Camm, AJ (2017). Thorough QT study of the effect of intravenous amisulpride on QTc interval in Caucasian and Japanese healthy subjects. British journal of clinical pharmacology 83(2) 339–348. DOI:10.1111/bcp.13128 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27618796