.Pharmacolibrary.Drugs.ATC.N.N05AX14

Information

Iloperidone is an atypical antipsychotic medication primarily used for the treatment of schizophrenia in adults. It acts as an antagonist at dopamine D2 and serotonin 5-HT2A receptors and is approved for use in several countries, including the United States.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following single and multiple oral dose administration of iloperidone.

References

1. Crabtree, BL, & Montgomery, J (2011). Iloperidone for the management of adults with schizophrenia. Clinical therapeutics 33(3) 330–345. DOI:10.1016/j.clinthera.2011.03.006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21600386

2. Rado, J, & Janicak, PG (2012). Pharmacological and clinical profile of recently approved second-generation antipsychotics: implications for treatment of schizophrenia in older patients. Drugs & aging 29(10) 783–791. DOI:10.1007/s40266-012-0009-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23018584

Revisions

• 06/2025 initial generated model