| name: | Clobazam | |
| ATC code: | N05BA09 | route: | oral | 
| compartments: | 1 | |
| dosage: | 20 | mg | 
| volume of distribution: | 1.3 | L | 
| clearance: | 1.7 | L/h | 
| other parameters in model implementation | ||
Clobazam is a benzodiazepine derivative used primarily as an adjunctive therapy in the treatment of seizures associated with Lennox-Gastaut syndrome and other epileptic disorders. It is also used for short-term relief of severe anxiety. Clobazam is approved and widely used today for epilepsy management.
Pharmacokinetic parameters in healthy adult volunteers following single oral dose administration.
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Tolbert, D, et al., & Ette, EI (2016). Drug-metabolism mechanism: Knowledge-based population pharmacokinetic approach for characterizing clobazam drug-drug interactions. Journal of clinical pharmacology 56(3) 365–374. DOI:10.1002/jcph.603 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26224203
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