.Pharmacolibrary.Drugs.ATC.N.N05BE01

Information

name:Buspirone
ATC code:N05BE01
route:oral
n-compartments1

Buspirone is an anxiolytic medication, primarily approved and used for the management of generalized anxiety disorder (GAD). It acts as a serotonin 5-HT1A receptor partial agonist and has minimal sedative or dependency potential compared to benzodiazepines. Buspirone is approved by regulatory agencies and commonly prescribed for anxiety disorders.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers (both sexes), after a single oral dose administration.

References

  1. Gammans, RE, et al., & LaBudde, JA (1989). Pharmacokinetics of buspirone in elderly subjects. Journal of clinical pharmacology 29(1) 72–78. DOI:10.1002/j.1552-4604.1989.tb03240.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/2708551

  2. Small, BG, et al., & Johnson, TN (2023). Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis. Clinical pharmacology and therapeutics 114(6) 1264–1273. DOI:10.1002/cpt.3032 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37620290

Revisions


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