.Pharmacolibrary.Drugs.ATC.N.N05CC01

Information

name:ChloralHydrate
ATC code:N05CC01
route:oral
n-compartments1

Chloral hydrate is a sedative and hypnotic drug historically used for the short-term treatment of insomnia and to calm patients before surgery. It is now largely obsolete and has largely been replaced by safer alternatives, but may still be used in some pediatric sedation protocols and for certain procedures.

Pharmacokinetics

Pharmacokinetics reported in healthy adult subjects following oral administration.

References

  1. Allegaert, K, et al., & Devlieger, H (2005). Pharmacodynamics of chloral hydrate in former preterm infants. European journal of pediatrics 164(7) 403–407. DOI:10.1007/s00431-005-1648-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15798911

  2. Mayers, DJ, et al., & Kasian, GF (1991). Chloral hydrate disposition following single-dose administration to critically ill neonates and children. Developmental pharmacology and therapeutics 16(2) 71–77. PUBMED:https://pubmed.ncbi.nlm.nih.gov/1914781

Revisions

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