.Pharmacolibrary.Drugs.ATC.N.N05CM05_1

Information

name:Scopolamine_1
ATC code:N05CM05_1
route:transdermal
n-compartments1

Scopolamine is an anticholinergic agent used to prevent motion sickness and postoperative nausea/vomiting. It blocks the action of acetylcholine on smooth muscles, glands, and in the central nervous system.

Pharmacokinetics

Pharmacokinetics reported in healthy males and females after transdermal administration (1.5 mg/patch, delivering approximately 1 mg over 3 days).

References

  1. Delgado-Charro, MB, & Guy, RH (2014). Effective use of transdermal drug delivery in children. Advanced drug delivery reviews 73 63–82. DOI:10.1016/j.addr.2013.11.014 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24333231

  2. Berner, B, & John, VA (1994). Pharmacokinetic characterisation of transdermal delivery systems. Clinical pharmacokinetics 26(2) 121–134. DOI:10.2165/00003088-199426020-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8162656

  3. Guay, DR (2003). Clinical pharmacokinetics of drugs used to treat urge incontinence. Clinical pharmacokinetics 42(14) 1243–1285. DOI:10.2165/00003088-200342140-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14606931

Revisions

Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos