.Pharmacolibrary.Drugs.ATC.N.N06AA07 .Pharmacolibrary.Drugs.ATC.N.N06AA07| name: | Lofepramine | |
| ATC code: | N06AA07 | route: | oral |
| compartments: | 1 | |
| dosage: | 70 | mg |
| volume of distribution: | 22 | L |
| clearance: | 1200 | mL/min |
| other parameters in model implementation | ||
Lofepramine is a tricyclic antidepressant (TCA) primarily used in the treatment of major depressive disorder. It is considered to have a slightly more favorable side effect profile compared to other TCAs. Lofepramine is approved and is still prescribed in certain countries, including the UK, for depression management.
Estimated typical adult pharmacokinetic parameters for oral administration; direct publications of detailed compartmental PK parameters for lofepramine are lacking.