| name: | Protriptyline | |
| ATC code: | N06AA11 | route: | oral | 
| compartments: | 1 | |
| dosage: | 15 | mg | 
| volume of distribution: | 20 | L | 
| clearance: | 0.88 | L/h/kg | 
| other parameters in model implementation | ||
Protriptyline is a tricyclic antidepressant (TCA) used primarily for the treatment of depression and occasionally for conditions such as ADHD and narcolepsy. It is less sedating than other TCAs and is no longer a first-line therapy, but still clinically used in some cases.
Estimates based on general TCA pharmacokinetics and available secondary resources for adult subjects; specific published compartmental PK studies on protriptyline are lacking.