.Pharmacolibrary.Drugs.ATC.N.N06AB05 .Pharmacolibrary.Drugs.ATC.N.N06AB05| name: | Paroxetine |
| ATC code: | N06AB05 | route: | oral |
| n-compartments | 1 |
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) commonly used for the treatment of major depressive disorder, anxiety disorders, obsessive-compulsive disorder, and other mood disorders. It is an approved and widely-used antidepressant.
Pharmacokinetic parameters in healthy adult volunteers after a single oral dose.
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Chen, R, et al., & Hu, P (2017). Polymorphism in CYP2D6 affects the pharmacokinetics and dose escalation of paroxetine controlled-release tablet in healthy Chinese subjects. International journal of clinical pharmacology and therapeutics 55(11) 853–860. DOI:10.5414/CP203008 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28933337
Chen, R, et al., & Hu, P (2015). Cytochrome P450 2D6 genotype affects the pharmacokinetics of controlled-release paroxetine in healthy Chinese subjects: comparison of traditional phenotype and activity score systems. European journal of clinical pharmacology 71(7) 835–841. DOI:10.1007/s00228-015-1855-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25967538