.Pharmacolibrary.Drugs.ATC.N.N06AX07 .Pharmacolibrary.Drugs.ATC.N.N06AX07| name: | Minaprine | |
| ATC code: | N06AX07 | route: | oral |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 16 | L/h |
| other parameters in model implementation | ||
Minaprine is a reversible inhibitor of monoamine oxidase A (MAO-A) and has additional serotonergic and dopaminergic activity. It was marketed as an antidepressant drug in France but has since been withdrawn due to concerns regarding its safety profile, particularly risk of convulsions. It is not approved or used clinically today.
Pharmacokinetic parameters estimated for a typical healthy adult after oral administration as no comprehensive PK human studies with full compartmental model parameters published.