.Pharmacolibrary.Drugs.ATC.N.N06AX26 .Pharmacolibrary.Drugs.ATC.N.N06AX26| name: | Vortioxetine |
| ATC code: | N06AX26 | route: | oral |
| n-compartments | 2 |
Vortioxetine is an antidepressant approved for the treatment of major depressive disorder (MDD) in adults. It acts as a serotonin modulator and stimulator, functioning as a serotonin reuptake inhibitor and agonist or antagonist at various serotonin receptors. It is currently approved and in use for the treatment of depression in many countries.
Pharmacokinetic parameters as reported in healthy adult volunteers after single and multiple oral doses of vortioxetine.
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Naik, H, et al., & Areberg, J (2016). A Population Pharmacokinetic-Pharmacodynamic Meta-Analysis of Vortioxetine in Patients with Major Depressive Disorder. Basic & clinical pharmacology & toxicology 118(5) 344–355. DOI:10.1111/bcpt.12513 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26525043