| name: | Citicoline_1 | |
| ATC code: | N06BX06_1 | route: | intravenous | 
| compartments: | 2 | |
| dosage: | 1000 | mg | 
| volume of distribution: | 1.14 | L | 
| clearance: | 0.26 | L/h/kg | 
| other parameters in model implementation | ||
Citicoline (CDP-choline) is an endogenous nucleotide involved in the biosynthesis of phosphatidylcholine, a component of cell membranes. It is used as a neuroprotective agent in the management of stroke, traumatic brain injury, and cognitive impairment. It is available as a supplement/medication in some countries, but its clinical efficacy remains debated and it is not FDA approved in the United States.
Pharmacokinetic parameters in healthy adults following intravenous bolus injection.