name: | NeostigmineCombinations |
ATC code: | N07AA51 | route: | intravenous |
n-compartments | 2 |
Neostigmine is a reversible acetylcholinesterase inhibitor used to enhance neuromuscular transmission. It is commonly used in the treatment of myasthenia gravis, reversal of non-depolarizing neuromuscular blockade post-surgery, and sometimes in the management of postoperative ileus and urinary retention. In combination products (ATC: N07AA51), it is typically combined with other cholinesterase inhibitors or anticholinergic agents. Neostigmine and its combinations are still approved for use today in many countries.
General adult population, both sexes, no specific disease or condition distinction, pharmacokinetic parameters derived primarily from pharmacokinetic studies in healthy volunteers with combination formulations.