.Pharmacolibrary.Drugs.ATC.N.N07CA03 .Pharmacolibrary.Drugs.ATC.N.N07CA03| name: | Flunarizine | |
| ATC code: | N07CA03 | route: | oral |
| compartments: | 2 | |
| dosage: | 10 | mg |
| volume of distribution: | 78 | L |
| clearance: | 220 | mL/h/kg |
| other parameters in model implementation | ||
Flunarizine is a selective calcium entry blocker with antihistaminic, sedative, and vasodilating properties. It is mainly used as prophylactic treatment for migraine, and in some cases for vestibular disorders and vertigo. It is not approved in the United States but is available in some European and Asian countries.
Pharmacokinetic parameters reported in healthy adult volunteers following oral administration of a single dose.
Paton, DM, & Webster, DR (1985). Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines). Clinical pharmacokinetics 10(6) 477–497. DOI:10.2165/00003088-198510060-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2866055