.Pharmacolibrary.Drugs.ATC.P.P01BE01_1 .Pharmacolibrary.Drugs.ATC.P.P01BE01_1| name: | Artemisinin_1 |
| ATC code: | P01BE01_1 | route: | intravenous |
| n-compartments | 2 |
Artemisinin is a sesquiterpene lactone isolated from the plant Artemisia annua, used primarily as an antimalarial agent. It is effective against Plasmodium falciparum malaria and is used in combination therapies for treatment. Artemisinin and its derivatives are widely used and recommended by the World Health Organization (WHO) for malaria treatment.
Pharmacokinetic parameters reported for healthy adult volunteers after intravenous bolus administration.
Cen, YY, et al., & Zhou, H (2018). [Research progress on pharmacokinetics and pharmacological activities of artesunate]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 43(19) 3970–3978. DOI:10.19540/j.cnki.cjcmm.20180726.010 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30453725
Sinou, V, et al., & Parzy, D (2008). Pharmacokinetics of artesunate in the domestic pig. The Journal of antimicrobial chemotherapy 62(3) 566–574. DOI:10.1093/jac/dkn231 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18559353
Zaloumis, SG, et al., & Simpson, JA (2021). Development and Validation of an . Antimicrobial agents and chemotherapy 65(6) –. DOI:10.1128/AAC.02346-20 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33685888