.Pharmacolibrary.Drugs.ATC.P.P01BX02_1 .Pharmacolibrary.Drugs.ATC.P.P01BX02_1| name: | ArterolaneAndPiperaquine_1 | |
| ATC code: | P01BX02_1 | route: | oral |
| compartments: | 3 | |
| dosage: | 750 | mg |
| volume of distribution: | 880 | L |
| clearance: | 5 | L/h |
| other parameters in model implementation | ||
Arterolane and piperaquine is a fixed-dose combination antimalarial, currently used for the treatment of malaria, particularly in South Asia.
Pharmacokinetic parameters for piperaquine in healthy adult volunteers after oral administration of 750 mg piperaquine phosphate plus 150 mg arterolane maleate.
Valecha, N, et al., & Anvikar, AR (2016). Comparison of the safety and efficacy of fixed-dose combination of arterolane maleate and piperaquine phosphate with chloroquine in acute, uncomplicated Plasmodium vivax malaria: a phase III, multicentric, open-label study. Malaria journal 15 42–None. DOI:10.1186/s12936-016-1084-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26818020