.Pharmacolibrary.Drugs.ATC.P.P02CA01 .Pharmacolibrary.Drugs.ATC.P.P02CA01| name: | Mebendazole |
| ATC code: | P02CA01 | route: | oral |
| n-compartments | 1 |
Mebendazole is a broad-spectrum anthelmintic drug used for the treatment of various helminthic infections such as ascariasis, hookworm, whipworm, and pinworm. It is listed as an essential medicine by the WHO and remains an approved and widely used medication for parasitic worm infections in both adults and children.
Pharmacokinetic parameters reported for healthy adult volunteers following a single oral dose.
Ceballos, L, et al., & Lanusse, CE (2018). Assessment of serum pharmacokinetics and urinary excretion of albendazole and its metabolites in human volunteers. PLoS neglected tropical diseases 12(1) e0005945–None. DOI:10.1371/journal.pntd.0005945 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29346367
Villaverde, C, et al., & Prieto, JG (1992). Albendazole and mebendazole uptake by isolated enterocytes. Developmental pharmacology and therapeutics 19(1) 27–31. DOI:10.1159/000457459 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1307343