.Pharmacolibrary.Drugs.ATC.R.R01AA04 .Pharmacolibrary.Drugs.ATC.R.R01AA04| name: | Phenylephrine |
| ATC code: | R01AA04 | route: | oral |
| n-compartments | 1 |
Phenylephrine is a selective α1-adrenergic receptor agonist used primarily as a decongestant, to increase blood pressure in hypotensive states, and as a mydriatic agent. It is commonly used in over-the-counter cold and allergy medications, and as a vasopressor in clinical settings. It is still approved and widely used today.
Pharmacokinetic parameters in healthy adult volunteers following oral administration.
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Atkinson, HC, et al., & Anderson, BJ (2015). Increased bioavailability of phenylephrine by co-administration of acetaminophen: results of four open-label, crossover pharmacokinetic trials in healthy volunteers. European journal of clinical pharmacology 71(2) 151–158. DOI:10.1007/s00228-014-1788-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25475358
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