.Pharmacolibrary.Drugs.ATC.R.R01AA14 .Pharmacolibrary.Drugs.ATC.R.R01AA14| name: | Epinephrine |
| ATC code: | R01AA14 | route: | intranasal |
| n-compartments | 1 |
Epinephrine (also known as adrenaline) is a naturally occurring catecholamine hormone and neurotransmitter used primarily in emergency medicine. It is indicated for the treatment of severe allergic reactions (anaphylaxis), cardiac arrest, and as a vasoconstrictor in shock. It is approved and widely used today in various clinical settings.
Pharmacokinetic parameters estimated for adult healthy individuals. No direct publication was found for intranasal/ATC R01AA14-specific administration; values are extrapolated from general human PK and alternative routes (intramuscular/intravenous) as reference.
Yoo, H, et al., & Jusko, WJ (2015). Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects. European journal of clinical pharmacology 71(10) 1197–1207. DOI:10.1007/s00228-015-1913-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26233335