.Pharmacolibrary.Drugs.ATC.R.R01AB02 .Pharmacolibrary.Drugs.ATC.R.R01AB02| name: | Naphazoline | |
| ATC code: | R01AB02 | route: | topical |
| compartments: | 1 | |
| dosage: | 0.05 | mg |
| volume of distribution: | 3.0 | L |
| clearance: | 0.7 | L/h/kg |
| other parameters in model implementation | ||
Naphazoline is an imidazoline derivative and a sympathomimetic vasoconstrictor primarily used as a topical decongestant in ophthalmology for eye redness and in nasal preparations for relief of nasal congestion. It acts as an alpha-adrenergic receptor agonist. Naphazoline has been approved and is still used in many over-the-counter ophthalmic and nasal products.
Estimated pharmacokinetic model parameters for topical ocular or nasal administration in adult humans; no pharmacokinetic studies found quantifying naphazoline PK parameters in the published literature.