.Pharmacolibrary.Drugs.ATC.R.R01AB05 .Pharmacolibrary.Drugs.ATC.R.R01AB05| name: | Ephedrine | |
| ATC code: | R01AB05 | route: | oral |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 2.6 | L |
| clearance: | 130 | ml/min |
| other parameters in model implementation | ||
Ephedrine is a sympathomimetic amine used as a decongestant, bronchodilator, and central nervous system stimulant. It is commonly used to treat hypotension during anesthesia and historically as a treatment for asthma and nasal congestion. Its use is currently limited in many countries due to potential for misuse and adverse cardiovascular effects.
Pharmacokinetic parameters in healthy adult volunteers following oral administration.
Howard, DR, et al., & Agrawala, P (2005). Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults. Current medical research and opinion 21(5) 769–776. DOI:10.1185/030079905x43703 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15969876