.Pharmacolibrary.Drugs.ATC.R.R01AX03

Information

name:IpratropiumBromide
ATC code:R01AX03
route:inhalation
n-compartments2

Ipratropium bromide is a short-acting anticholinergic (muscarinic antagonist) bronchodilator that is used for the management of bronchospasm associated with chronic obstructive pulmonary disease (COPD) and, to a lesser extent, asthma. It is administered via inhalation and is currently an approved medication in many countries.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers following single inhalation dose.

References

  1. Panning, CA, & DeBisschop, M (2003). Tiotropium: an inhaled, long-acting anticholinergic drug for chronic obstructive pulmonary disease. Pharmacotherapy 23(2) 183–189. DOI:10.1592/phco.23.2.183.32082 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12587807

  2. MacGregor, TR, et al., & Wood, CC (2016). Efficiency of Ipratropium Bromide and Albuterol Deposition in the Lung Delivered via a Soft Mist Inhaler or Chlorofluorocarbon Metered-Dose Inhaler. Clinical and translational science 9(2) 105–113. DOI:10.1111/cts.12387 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26945929

  3. Lee, YH, et al., & Noh, GJ (2016). Efficiency of a New Mesh-Type Nebulizer (NE-SM1 NEPLUS) for Intrapulmonary Delivery of Ipratropium Bromide in Surgical Patients. Basic & clinical pharmacology & toxicology 118(4) 313–319. DOI:10.1111/bcpt.12499 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26440415

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos