.Pharmacolibrary.Drugs.ATC.R.R02AA05 .Pharmacolibrary.Drugs.ATC.R.R02AA05| name: | Chlorhexidine | |
| ATC code: | R02AA05 | route: | topical |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | |
| other parameters in model implementation | ||
Chlorhexidine is a broad-spectrum antiseptic and disinfectant commonly used for skin disinfection, oral rinses, and preoperative cleaning. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine remains a widely used and approved topical antiseptic today.
No published pharmacokinetic model parameters for systemic use in humans; parameters below are estimated or not applicable, as chlorhexidine is used topically or as an oral rinse and systemic absorption is minimal.
Lim, SY, et al., & Heard, CM (2020). Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International journal of pharmaceutics 573 118860–None. DOI:10.1016/j.ijpharm.2019.118860 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31759104