.Pharmacolibrary.Drugs.ATC.R.R03BB03 .Pharmacolibrary.Drugs.ATC.R.R03BB03| name: | StramoniPreparations |
| ATC code: | R03BB03 | route: | inhalation |
| n-compartments | 1 |
Stramoni preparations are derived from the plant Datura stramonium, containing tropane alkaloids such as atropine, hyoscyamine, and scopolamine. Historically, they were used as bronchodilators in the treatment of asthma and other respiratory disorders, primarily in the form of inhaled powders or cigarettes. Due to significant toxicity and safer alternatives, such preparations are no longer in common or approved therapeutic use.
No clinical pharmacokinetic studies or precise population data for stramoni preparations as a mixture exist; parameter estimates are extrapolated from known pharmacokinetics of the major tropane alkaloid component (atropine) in healthy adult subjects following inhaled administration.
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