.Pharmacolibrary.Drugs.ATC.R.R03CC02_1

Information

Salbutamol (also known as albuterol) is a short-acting β2 adrenergic receptor agonist used for the rapid relief and prevention of bronchospasm in conditions such as asthma and COPD. It is globally approved and widely utilized in acute symptomatic management as well as prevention of exercise-induced bronchospasm.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following intravenous administration.

References

1. Vet, NJ, et al., & de Hoog, M (2020). Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus. Clinical pharmacokinetics 59(2) 257–264. DOI:10.1007/s40262-019-00811-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/31432470

2. Marques, L, & Vale, N (2024). Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients. Pharmaceutics 17(1) –. DOI:10.3390/pharmaceutics17010039 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39861686

3. Antoniu, S (2014). Bedoradrine for treating asthma and chronic obstructive pulmonary disease. Expert opinion on investigational drugs 23(8) 1149–1156. DOI:10.1517/13543784.2014.928284 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24938936

Revisions

• 06/2025 initial generated model