.Pharmacolibrary.Drugs.ATC.R.R05CB01

Information

name:Acetylcysteine
ATC code:R05CB01
route:oral
n-compartments1

Acetylcysteine (N-acetylcysteine, NAC) is a mucolytic agent used to break down mucus, particularly in the lungs. It is also used as an antidote for acetaminophen (paracetamol) overdose. Approved and widely used in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers after oral administration.

References

  1. Forrest, JA, et al., & Prescott, LF (1982). Clinical pharmacokinetics of paracetamol. Clinical pharmacokinetics 7(2) 93–107. DOI:10.2165/00003088-198207020-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7039926

  2. Aggarwal, R, et al., & Chauhan, MK (2020). Treatment and management strategies of onychomycosis. Journal de mycologie medicale 30(2) 100949–None. DOI:10.1016/j.mycmed.2020.100949 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32234349

  3. Petkova, T, et al., & Milanova, A (2022). Population Pharmacokinetics of Doxycycline, Administered Alone or with N-Acetylcysteine, in Chickens with Experimental . Pharmaceutics 14(11) –. DOI:10.3390/pharmaceutics14112440 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36432632

Revisions

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