.Pharmacolibrary.Drugs.ATC.R.R06AA10 .Pharmacolibrary.Drugs.ATC.R.R06AA10| name: | Trimethobenzamide | |
| ATC code: | R06AA10 | route: | oral |
| compartments: | 1 | |
| dosage: | 300 | mg |
| volume of distribution: | 3.5 | L |
| clearance: | 30 | L/h |
| other parameters in model implementation | ||
Trimethobenzamide is an antiemetic medication used to prevent and treat nausea and vomiting. It functions primarily as a dopamine (D2) receptor antagonist. Trimethobenzamide has been used in clinical practice for decades but is less commonly used today compared to other antiemetics. It is mainly approved for short-term use in the management of postoperative or toxin-induced nausea and vomiting.
Estimated pharmacokinetic parameters for adults, based on limited available literature and standard clinical dosing. Specific clinical PK studies are lacking.