.Pharmacolibrary.Drugs.ATC.R.R06AE09

Information

Levocetirizine is a selective, non-sedating antihistamine used primarily for the symptomatic relief of allergic rhinitis (including hay fever) and chronic idiopathic urticaria. It is the levo-enantiomer of cetirizine and is available as an approved medication in many countries for both adults and children.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult subjects following oral administration of a single 5 mg dose.

References

1. Simons, FE (2005). Population pharmacokinetics of levocetirizine in very young children: the pediatricians' perspective. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 16(2) 97–103. DOI:10.1111/j.1399-3038.2005.00240.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/15787865

2. Ino, H, et al., & Fukase, H (2014). Comparison of levocetirizine pharmacokinetics after single doses of levocetirizine oral solution and cetirizine dry syrup in healthy Japanese male subjects. Journal of drug assessment 3(1) 38–42. DOI:10.3109/21556660.2014.928302 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27536452

3. Hussein, Z, et al., & Stockis, A (2005). Retrospective population pharmacokinetics of levocetirizine in atopic children receiving cetirizine: the ETAC study. British journal of clinical pharmacology 59(1) 28–37. DOI:10.1111/j.1365-2125.2005.02242.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/15606437

Revisions

• 06/2025 initial generated model