.Pharmacolibrary.Drugs.ATC.R.R06AX18

Information

name:Acrivastine
ATC code:R06AX18
route:oral
compartments:1
dosage:8mg
volume of distribution:65L
clearance:8.6L/h
other parameters in model implementation

Acrivastine is a second-generation non-sedating antihistamine used for the symptomatic relief of allergic conditions such as hay fever, urticaria, and other allergic rhinitis symptoms. It is commonly available in combination with pseudoephedrine and is approved for use in several countries.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult subjects after a single oral dose of 8 mg acrivastine.

References

  1. Simons, FE (2002). Comparative pharmacology of H1 antihistamines: clinical relevance. The American journal of medicine 113 Suppl 9A 38S–46S. DOI:10.1016/s0002-9343(02)01436-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12517581

  2. Simons, FE, & Simons, KJ (1999). Clinical pharmacology of new histamine H1 receptor antagonists. Clinical pharmacokinetics 36(5) 329–352. DOI:10.2165/00003088-199936050-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10384858

Revisions


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