.Pharmacolibrary.Drugs.ATC.R.R06AX22

Information

name:Ebastine
ATC code:R06AX22
route:oral
n-compartments1

Ebastine is a second-generation antihistamine used to treat allergic conditions such as allergic rhinitis and chronic idiopathic urticaria. It inhibits peripheral H1 receptors and has minimal sedative effects. Ebastine is approved in several countries for allergy treatment.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult subjects after a single oral dose.

References

  1. Simons, FE (2002). Comparative pharmacology of H1 antihistamines: clinical relevance. The American journal of medicine 113 Suppl 9A 38S–46S. DOI:10.1016/s0002-9343(02)01436-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12517581

  2. Chen, K, & Sun, Y (2025). Development and Optimization of Oral Dissolution Films for Enhanced Delivery of Ebastine-Loaded Solid Lipid Nanoparticles. International journal of nanomedicine 20 6963–6981. DOI:10.2147/IJN.S521504 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40462833

  3. Simons, FE, & Simons, KJ (1999). Clinical pharmacology of new histamine H1 receptor antagonists. Clinical pharmacokinetics 36(5) 329–352. DOI:10.2165/00003088-199936050-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10384858

Revisions

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