.Pharmacolibrary.Drugs.ATC.S.S01AA09

Information

Tetracycline is a broad-spectrum antibiotic from the tetracycline class, historically used to treat a variety of bacterial infections including respiratory tract infections, urinary tract infections, and acne. Its use has dramatically decreased due to resistance and the availability of newer agents, but it is still used in some settings.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects after oral administration.

References

1. Tao, RE, et al., & Feldman, SR (2023). Oral Tetracycline-Class Drugs in Dermatology: Impact of Food Intake on Absorption and Efficacy. Antibiotics (Basel, Switzerland) 12(7) –. DOI:10.3390/antibiotics12071152 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37508248

2. Thompson, EJ, et al., & Hornik, CP (2019). Population Pharmacokinetics of Doxycycline in Children. Antimicrobial agents and chemotherapy 63(12) –. DOI:10.1128/AAC.01508-19 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31548185

3. Rodvold, KA, et al., & Pai, MP (2020). Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics. Clinical pharmacokinetics 59(4) 409–425. DOI:10.1007/s40262-019-00843-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31773505

Revisions

• 06/2025 initial generated model