name: | Prednisolone |
ATC code: | S01BA04 | route: | oral |
n-compartments | 2 |
Prednisolone is a synthetic glucocorticoid corticosteroid drug that exhibits anti-inflammatory and immunosuppressive properties. It is primarily used for the treatment of a wide range of inflammatory and autoimmune diseases, such as asthma, rheumatoid arthritis, and allergic reactions, as well as certain eye conditions. Prednisolone is approved for use today in various formulations, including ophthalmic preparations.
Pharmacokinetic data reported in healthy adult subjects after a single oral administration.
de Truchis, C, et al., & Boyer, O (2023). Prednisolone pharmacokinetics after oral prednisone administration in paediatric patients with kidney transplant. British journal of clinical pharmacology 89(5) 1532–1540. DOI:10.1111/bcp.15610 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36510685
Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270
Yoshida, K, et al., & Chanu, P (2021). Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients. Journal of clinical pharmacology 61(12) 1579–1591. DOI:10.1002/jcph.1942 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34273118