name: | Pilocarpine |
ATC code: | S01EB01 | route: | oral |
n-compartments | 1 |
Pilocarpine is a muscarinic cholinergic agonist primarily used in ophthalmology to treat conditions like glaucoma and to induce miosis. It is also utilized as a sialogogue for xerostomia in some patients. The drug is approved and still in clinical use, with topical ocular and oral formulations available.
Estimated pharmacokinetic parameters for adult healthy humans, for oral administration as oral tablet.
Muthumariappan, S, et al., & Ferreira, JN (2019). Localized Delivery of Pilocarpine to Hypofunctional Salivary Glands through Electrospun Nanofiber Mats: An Ex Vivo and In Vivo Study. International journal of molecular sciences 20(3) –. DOI:10.3390/ijms20030541 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30696017