.Pharmacolibrary.Drugs.ATC.S.S01EB06

Information

Neostigmine is a reversible acetylcholinesterase inhibitor used to treat myasthenia gravis, reverse the effects of non-depolarizing muscle relaxants after surgery, and manage postoperative ileus and urinary retention. It is a well-established drug and remains in clinical use today, especially in anesthesiology.

Pharmacokinetics

Pharmacokinetic parameters reported for adult healthy volunteers after intravenous administration.

References

1. Keating, GM (2016). Sugammadex: A Review of Neuromuscular Blockade Reversal. Drugs 76(10) 1041–1052. DOI:10.1007/s40265-016-0604-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27324403

2. Onrust, SV, & Foster, RH (1999). Rapacuronium bromide: a review of its use in anaesthetic practice. Drugs 58(5) 887–918. DOI:10.2165/00003495-199958050-00011 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10595867

Revisions

• 06/2025 initial generated model