.Pharmacolibrary.Drugs.ATC.S.S01FA02_1

Information

name:Scopolamine_1
ATC code:S01FA02_1
route:oral
n-compartments2

Scopolamine, also known as hyoscine, is a tropane alkaloid anticholinergic drug used primarily for the prevention of motion sickness, postoperative nausea and vomiting, and as a mydriatic and cycloplegic agent in ophthalmology. It is available in various formulations including oral, transdermal, and parenteral administration. Scopolamine is still in clinical use today, mainly for its antiemetic properties and ophthalmological purposes.

Pharmacokinetics

Pharmacokinetic parameters in healthy adults after oral administration.

References

  1. Tytgat, GN (2007). Hyoscine butylbromide: a review of its use in the treatment of abdominal cramping and pain. Drugs 67(9) 1343–1357. DOI:10.2165/00003495-200767090-00007 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17547475

  2. Guay, DR (2003). Clinical pharmacokinetics of drugs used to treat urge incontinence. Clinical pharmacokinetics 42(14) 1243–1285. DOI:10.2165/00003088-200342140-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14606931

  3. Rompicherla, SKL, et al., & Rao, CM (2021). Pharmacokinetic and pharmacodynamic evaluation of nasal liposome and nanoparticle based rivastigmine formulations in acute and chronic models of Alzheimer's disease. Naunyn-Schmiedeberg's archives of pharmacology 394(8) 1737–1755. DOI:10.1007/s00210-021-02096-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34086100

Revisions


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