.Pharmacolibrary.Drugs.ATC.S.S01GX07 .Pharmacolibrary.Drugs.ATC.S.S01GX07| name: | Azelastine | |
| ATC code: | S01GX07 | route: | ophthalmic |
| compartments: | 1 | |
| dosage: | 0.5 | mg |
| volume of distribution: | 14.5 | L |
| clearance: | 0.5 | L/h/kg |
| other parameters in model implementation | ||
Azelastine is a potent second-generation antihistamine with additional anti-inflammatory effects, used mainly for the treatment of allergic conjunctivitis and allergic rhinitis. It is currently approved for ophthalmic and intranasal use globally.
Pharmacokinetic parameters in healthy adult volunteers following ophthalmic administration.
Simons, FE, & Simons, KJ (1999). Clinical pharmacology of new histamine H1 receptor antagonists. Clinical pharmacokinetics 36(5) 329–352. DOI:10.2165/00003088-199936050-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10384858