.Pharmacolibrary.Drugs.ATC.S.S01JA51

Information

name:FluoresceinCombinations
ATC code:S01JA51
route:intravenous
n-compartments2

Fluorescein is a synthetic organic compound and fluorophore used as a diagnostic agent in ophthalmology for visualizing corneal abrasions, retinal blood flow, and other eye conditions. It is usually administered topically or intravenously. In combinations (ATC S01JA51), it is used for diagnostic purposes in combination with other agents such as local anaesthetics. Fluorescein is an approved drug and widely used in current clinical practice.

Pharmacokinetics

No published pharmacokinetic (PK) data specific for fluorescein, combinations (ATC S01JA51) was found. PK parameters are estimated based on intravenous administration of fluorescein in healthy adults.

References

  1. Thorling, CA, et al., & Roberts, MS (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug metabolism and disposition: the biological fate of chemicals 43(1) 154–162. DOI:10.1124/dmd.114.060848 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25380806

  2. Gosain, AK, et al., & Upton, RA (1991). Relationship between skin fluorescence and blood flow in normal and in chronically ischemic subjects dosed with fluorescein. Journal of pharmaceutical sciences 80(7) 632–637. DOI:10.1002/jps.2600800704 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1941558

Revisions


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