.Pharmacolibrary.Drugs.ATC.S.S01XA26

Information

Riboflavin, also known as vitamin B2, is an essential water-soluble vitamin involved in energy metabolism in all living cells. It is used as a dietary supplement, in the treatment of riboflavin deficiency, and for prophylaxis of migraine headaches. For ophthalmic use (ATC code S01XA26), riboflavin is utilized as a photosensitizer in corneal collagen cross-linking procedures primarily for keratoconus. It is approved for these uses.

Pharmacokinetics

Estimated pharmacokinetic parameters for riboflavin, as specific peer-reviewed PK values for the ophthalmic ATC code S01XA26 use are not reported in published literature. Parameters based on general properties and estimated ocular bioavailability.

References

1. Price, MO, et al., & Price, FW (2018). Prospective Randomized Trial of Corneal Cross-linking Riboflavin Dosing Frequencies for Treatment of Keratoconus and Corneal Ectasia. Ophthalmology 125(4) 505–511. DOI:10.1016/j.ophtha.2017.10.034 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29203068

Revisions

• 06/2025 initial generated model