.Pharmacolibrary.Drugs.ATC.S.S02AA17_1

Information

name:Fosfomycin_1
ATC code:S02AA17_1
route:intravenous
n-compartments2

Fosfomycin is a broad-spectrum antibiotic, chiefly against Gram-negative bacteria and some Gram-positives. Used orally and intravenously, it is approved for monotherapy of uncomplicated urinary tract infection and, intravenously, for serious infections (off-label in some regions).

Pharmacokinetics

Pharmacokinetics of intravenous fosfomycin disodium in healthy adults after single infusion.

References

  1. Götz, KM, et al., & Lehr, T (2025). Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy. Antimicrobial agents and chemotherapy 69(6) e0177924–None. DOI:10.1128/aac.01779-24 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40323336

  2. Parker, SL, et al., & Roberts, JA (2015). Population Pharmacokinetics of Fosfomycin in Critically Ill Patients. Antimicrobial agents and chemotherapy 59(10) 6471–6476. DOI:10.1128/AAC.01321-15 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26239990

  3. Hüppe, T, et al., & Kreuer, S (2023). Population pharmacokinetic modeling of multiple-dose intravenous fosfomycin in critically ill patients during continuous venovenous hemodialysis. Scientific reports 13(1) 18132–None. DOI:10.1038/s41598-023-45084-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37875513

Revisions


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