.Pharmacolibrary.Drugs.ATC.S.S02AA30

Information

name:AntiinfectivesCombinations
ATC code:S02AA30
route:topical
compartments:1
dosage:3mg
volume of distribution:10L
clearance:0.1L/h
other parameters in model implementation

Antiinfectives, combinations (ATC code S02AA30) refer to ear preparations containing combinations of antibiotics for the treatment of infections of the ear, such as otitis externa or otitis media. These combinations may include antibiotics like neomycin, polymyxin B, or bacitracin, often used together for broader antimicrobial spectrum. Most of these combinations are topical and used primarily for local effect, and are approved for this indication.

Pharmacokinetics

Estimated pharmacokinetic parameters for typical topical otic antiinfective combinations in adults, as there are no published systemic PK data due to minimal systemic absorption after otic administration.

References

  1. Aggarwal, R, et al., & Chauhan, MK (2020). Treatment and management strategies of onychomycosis. Journal de mycologie medicale 30(2) 100949–None. DOI:10.1016/j.mycmed.2020.100949 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32234349

  2. Gupta, AK, & Studholme, C (2016). Novel investigational therapies for onychomycosis: an update. Expert opinion on investigational drugs 25(3) 297–305. DOI:10.1517/13543784.2016.1142529 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26765142

  3. Pickert, A, & Raimer, S (2009). An evaluation of dapsone gel 5% in the treatment of acne vulgaris. Expert opinion on pharmacotherapy 10(9) 1515–1521. DOI:10.1517/14656560903002097 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19505219

Revisions


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