.Pharmacolibrary.Drugs.ATC.S.S03CA06

Information

name:BetamethasoneAndAntiinfectives
ATC code:S03CA06
route:topical
compartments:1
dosage:0.5mg
volume of distribution:1.5L
clearance:0.1L/h/kg
other parameters in model implementation

Combination drug containing betamethasone, a potent synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties, and antiinfectives, typically for topical ophthalmic use to treat eye infections with an inflammatory component. Not widely approved as a fixed combination in all regions today, but used in some countries.

Pharmacokinetics

No published population pharmacokinetic studies of the fixed combination of betamethasone with antiinfectives (S03CA06) have been identified. Pharmacokinetic parameters estimated based on topical ophthalmic betamethasone data in healthy adults.

References

  1. Lim, SY, et al., & Heard, CM (2020). Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International journal of pharmaceutics 573 118860–None. DOI:10.1016/j.ijpharm.2019.118860 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31759104

Revisions


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