name: | Ethanol |
ATC code: | V03AB16 | route: | oral |
n-compartments | 1 |
Ethanol is a small organic molecule most commonly known as the active ingredient in alcoholic beverages. Medically, it has been used as an antidote for methanol and ethylene glycol poisoning, as a topical antiseptic, and for other limited medical purposes. It is not primarily used as a pharmaceutical agent in modern medicine, except in specific poisonings. It is not an approved therapeutic drug in general clinical practice today.
Mean population PK parameters in healthy adult volunteers after oral administration; values represent average data from literature.
Büsker, S, et al., & Fuhr, U (2023). Population Pharmacokinetics as a Tool to Reevaluate the Complex Disposition of Ethanol in the Fed and Fasted States. Journal of clinical pharmacology 63(6) 681–694. DOI:10.1002/jcph.2205 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36688276
Knych, HK, et al., & McKemie, DS (2024). Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses. Drug testing and analysis None –. DOI:10.1002/dta.3803 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39279026
Imbert, B, et al., & Simon, N (2016). Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation?. Therapeutic drug monitoring 38(2) 253–258. DOI:10.1097/FTD.0000000000000262 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26580099