name: | Hydroxocobalamin |
ATC code: | V03AB33 | route: | intravenous |
n-compartments | 2 |
Hydroxocobalamin is a form of vitamin B12, used as a therapeutic agent mainly in the treatment of vitamin B12 deficiency, pernicious anemia, and as an antidote for cyanide poisoning. It is approved by health authorities for these uses and is administered parenterally.
Pharmacokinetic parameters are from studies in healthy adult volunteers, single-dose intravenous administration.
Uhl, W, et al., & Kovar, A (2008). Changes in blood pressure after administration of hydroxocobalamin: relationship to changes in plasma cobalamins-(III) concentrations in healthy volunteers. Clinical toxicology (Philadelphia, Pa.) 46(6) 551–577. DOI:10.1080/15563650701829763 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18584369