.Pharmacolibrary.Drugs.ATC.V.V03AB35

Information

name:Sugammadex
ATC code:V03AB35
route:intravenous
n-compartments2

Sugammadex is a selective relaxant binding agent used to reverse neuromuscular blockade induced by rocuronium or vecuronium during surgical procedures under general anesthesia. It is approved and widely used in clinical practice for this indication.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers after single intravenous administration.

References

  1. de Kam, PJ, et al., & van den Heuvel, M (2015). Pharmacokinetics of sugammadex 16 mg/kg in healthy Chinese volunteers. International journal of clinical pharmacology and therapeutics 53(6) 456–461. DOI:10.5414/CP202234 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25907172

  2. Yuan, F, et al., & Joel Woolf, E (2022). Pharmacokinetics of Sugammadex: An Open-Label, 3-Period, Fixed-Sequence, 3-Single-Doses Study in Healthy Chinese Subjects. Clinical pharmacology in drug development 11(3) 333–340. DOI:10.1002/cpdd.1006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34939354

  3. Keating, GM (2016). Sugammadex: A Review of Neuromuscular Blockade Reversal. Drugs 76(10) 1041–1052. DOI:10.1007/s40265-016-0604-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27324403

Revisions

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