name: | AndexanetAlfa |
ATC code: | V03AB38 | route: | intravenous |
n-compartments | 2 |
Andexanet alfa is a recombinant modified human factor Xa decoy protein used to reverse the anticoagulant effects of direct and indirect factor Xa inhibitors, such as apixaban and rivaroxaban, in cases of life-threatening or uncontrolled bleeding. It is approved for use in adults by the FDA.
Pharmacokinetic model described for healthy adult volunteers following intravenous bolus followed by continuous infusion.