.Pharmacolibrary.Drugs.ATC.V.V03AE03 .Pharmacolibrary.Drugs.ATC.V.V03AE03| name: | LanthanumCarbonate |
| ATC code: | V03AE03 | route: | oral |
| n-compartments | 1 |
Lanthanum carbonate is a non-calcium, non-aluminum phosphate binder used to treat hyperphosphatemia in patients with end-stage renal disease. It reduces phosphate absorption from the gastrointestinal tract by binding dietary phosphate, forming insoluble lanthanum-phosphate complexes that are excreted in the feces. Lanthanum carbonate is approved and widely used for this purpose.
Pharmacokinetic profile in adult patients with chronic kidney disease; the drug is minimally absorbed from the gastrointestinal tract.
Damment, SJ, & Pennick, M (2008). Clinical pharmacokinetics of the phosphate binder lanthanum carbonate. Clinical pharmacokinetics 47(9) 553–563. DOI:10.2165/00003088-200847090-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18698878