.Pharmacolibrary.Drugs.ATC.V.V03AE07 .Pharmacolibrary.Drugs.ATC.V.V03AE07| name: | CalciumAcetate | |
| ATC code: | V03AE07 | route: | oral |
| compartments: | 1 | |
| dosage: | 667 | mg |
| volume of distribution: | 0.17 | L |
| clearance: | 0.06 | L/min |
| other parameters in model implementation | ||
Calcium acetate is an inorganic mineral supplement used primarily to control hyperphosphatemia (elevated blood phosphate levels) in patients with end-stage renal disease (ESRD) undergoing dialysis. It acts as a phosphate binder in the gastrointestinal tract, preventing absorption of dietary phosphate. The drug is approved and widely used in clinical practice today.
Estimated typical oral pharmacokinetic parameters for adult patients with end-stage renal disease, as no detailed compartmental pharmacokinetic model has been published.
Rekić, D, et al., & Hamrén, B (2021). Pharmacokinetics of Roxadustat: A Population Analysis of 2855 Dialysis- and Non-Dialysis-Dependent Patients with Chronic Kidney Disease. Clinical pharmacokinetics 60(6) 759–773. DOI:10.1007/s40262-020-00974-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/33486718